Tel: +44 (0) 118 930 3660

Special Offer 2

Protein L Affinity Chromatography


Protein A affinity chromatography is todays industry standard for capturing monoclonal antibodies. But some popular new antibody formats such as antibody fragments (Fabs), domain antibodies (DAbs), and single chain variable fragments (scFvs) do not bind to Protein A because they lack a fragment crystallisable (Fc) region.

Protein L is an easy solution for fast and efficient capturing of antibody related targets that do not bind to Protein A but have a kappa-light chain part that allows binding to Protein L. TOYOPEARL AF-rProtein L-650F resin from Tosoh Bioscience, is ideally suited for the purification of many antibody-related targets that cannot be purified by Protein A affinity chromatography.

TOYOPEARL® AF-r Protein L-650F, combines the rigid TOYOPEARL® polymer matrix with an engineered recombinant Protein L derived ligand. It provides:

• twice the capacity (for Fabs) of other Protein L media
• flexible cleaning options - excellent alkaline stability
• excellent pressure/flow characteristics
• increased throughput and reduced operating costs

For more information on TOYOPEARL® AF-rProtein L-650F resin and how it can benefit your antibody analysis

To download the brand new Tosoh Bioscience Process Media Catalogue

For further technical support

Why not join us for a FREE BioChromday taking place in Cambridge on the 25th April - contact Hichrom for full details and to register.

Tel:+44 (0)118 930 3660 Fax:+44 (0)118 932 3484

Terms and conditions

The above offers are:

  • only available on the listed columns and ranges
  • not available overseas
  • cannot be used in conjunction with any other offers, promotions or discounts
  • subject to availability
  • only valid for dates stated
  • available via email, tel or fax quoting appropriate ref. numbers
  • are not available to HPLC column distributors or HPLC column manufacturers.