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ProSwift polymeric monolithic media are particularly suited for the fast separation of proteins. Each monolith is a single cylindrical, sponge-like polymer rod containing an uninterrupted, interconnected network of flow-through channels of a specific pore size. These large channels combined with the monolith's nonporous surfaces result in fast mass transfer and high resolution. Columns for reversed-phase, ion-exchange and affinity chromatography are available.

  • Polymeric monolithic phases for RP, ion-exchange and affinity chromatography
  • Excellent stability over wide pH range
  • High loading capacity
  • Long column lifetimes

 ProSwift phase specifications

ProSwift PhaseBase MaterialFunctional GrouppH Range Capacity 
RP-1S Polystyrene-divinylbenzene monolith Phenyl 1 - 14 3.0mg/ml lysozyme
RP-2H Polystyrene-divinylbenzene monolith Phenyl 1 - 14 1.0mg/ml lysozyme
RP-3U Polystyrene-divinylbenzene monolith Phenyl 1 - 14 0.5mg/ml lysozyme
RP-4H Polystyrene-divinylbenzene monolith Phenyl 1 - 14 2.3mg/ml lysozyme
WCX-1S Polymethacrylate monolith Carboxylic acid 2- 12 23mg/ml lysozyme
SCX-1S Polymethacrylate monolith Sulphonic acid 2 - 12 30mg/ml lysozyme
WAX-1S Polymethacrylate monolith Tertiary amine (DEAE) 2 - 12 18mg/ml BSA
SAX-1S Polymethacrylate monolith Quaternary amine 2 - 12 18mg/ml BSA
Affinity Phase
ConA-1S Polymethacrylate monolith Concanavalin A ligands 5 - 8 12-16mg protein

ProSwift RP

ProSwift RP polystyrene-divinylbenzene monolith columns provide the unique advantages of high resolution at exceptionally high flow rates for fast protein separations and analysis. The monolith is bonded with phenyl functional groups and shows excellent stability over a wide pH range of 1 to 14. The specific pore size of the flow through channels range from small (1S), medium (2H and 4H) to very large (3U) sizes.

ProSwift IEX

ProSwift IEX monolithic columns provide excellent resolving power at high mass loading combined with fast analysis capability. Columns show excellent stability over a wide pH range.

ProSwift ConA-1S

The ProSwift ConA-1S affinity monolith column is designed for the highly efficient enrichment and purification of Concanavalin A binding glycans, glycopeptides and glycoproteins. It shows high capacity and high sample recovery. The column is reusable, and many enrichments and purifications are possible with minimal loss of capacity.


  • ProSwift reversed-phase monolith columns for protein analysis

Further technical information:


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