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ACE UltraCore

ACE UltraCore is a range of ultra-inert UHPLC/HPLC solid-core particle columns. The monodisperse particle distribution of these phases enables high efficiency to be combined with low column back pressure. UHPLC efficiency and performance can be achieved using conventional HPLC instrumentation. ACE UltraCore is available with SuperC18 and SuperPhenylHexyl bonding. Both phases are manufactured using proprietary Encapsulated Bonding Technology (EBT), which significantly increases ligand coverage of the silica surface and effectively eliminates the negative effects of unbonded silanol groups. This higher ligand coverage results in improved inertness, chromatographic performance and stability.

  • High efficiency 2.5 and 5um solid-core particles
  • SuperC18 and SuperPhenylHexyl phases
  • Extended pH stability (1.5 - 11.0)
  • Excellent for LC-MS applications

Material Specifications

ACE UltraCore phaseFunctional groupParticle size (um) Pore Size (A) Surface area (m2/g) Carbon load (%) pH rangeUSP listing
SuperC18C182.5951307.01.5 - 11.0L1
SuperPhenylHexylPhenylHexyl2.5951304.61.5 - 11.0L11
SuperC18C185951005.41.5 - 11.0L1
SuperPhenylHexylPhenylHexyl5951003.61.5 - 11.0L11

Both ACE UltraCore SuperC18 and SuperPhenylHexyl have an extended pH stability range of 1.5 to 11.0. This is advantageous for method development, enabling selectivity to be exploited at low, intermediate and high pH. In addition, these phases are specifically designed for use with LC-MS compatible buffers and exhibit extremely low phase bleed.

ACE UltraCore SuperC18 columns have been specifically designed for demanding MS applications. They are highly resistant to hydrolysis and contribute minimal background bleed, thus maximising MS signal intensity. In addition, eluent conditions can be adjusted across an extended pH range of 1.5 to 11, to maximise resolution and MS signal response. ACE UltraCore SuperC18 columns are available in microbore 0.5 and 1.0mm i.d. and analytical 2.1, 3.0 and 4.6mm i.d. A wide range of lengths from 20 to 250mm is available.

Literature available:

Further technical information