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HPLC/SFC columns by BRAND

Column Availability: Base Material

 
Silica is the most popular base material. It has a high physical strength & a surface area which is easily chemically modified to give phases suitable for use in a broad range of HPLC modes. However, silicas dissolve in water at pH >6.4 whilst bonded silicas are unstable at pH<2.6. Newer bonded silicas may have an extended pH range of 2-10 or higher. More recent innovations include the TYPE-CTM Silica range in which the silica surface is modified with a layer of silicon hydride.
Polymeric materials have minimal pH restrictions but are less physically stable and exhibit lower separation efficiencies than silica for small molecules. For large molecules such as proteins or synthetic polymers, their performance is comparable to that of silica based materials.
Graphitised carbon has high strength and excellent pH stability but cannot be modified. It can be expensive and is best used in unique selectivity
applications.
Zirconia (ZrO2) has the advantage of unique selectivity combined with extreme chemical and thermal stability (up to 200°C)
Titania (TiO2) is stable over a wide pH range and at elevated temperatures. In contrast to silica, the surface of titania is alkaline, which can be beneficial
in the analysis of basic drugs, but separation efficiencies are generally lower.
Alumina has greater pH stability than silica but cannot be easily chemically modified.

 

Hichrom supply >95% of the world's leading HPLC column brands.

Please contact Hichrom if the brand you require is not listed:

Hichrom supply >95% of the world's leading HPLC column brands.

Please contact Hichrom if the brand you require is not listed.

Hichrom Manufactured Columns - Column Dimensions

HiChromlength in cm
1 3 3.5 5 7.5 10 12.5 15 20 25 30 guard cartridge
ID in mm 1.0   Y Y Y Y Y Y Y Y Y Y Y
2.1 Y Y Y Y Y Y Y Y Y Y Y Y
3.2 Y Y Y Y Y Y Y Y Y Y Y Y
4.0 Y Y Y Y Y Y Y Y Y Y
4.6 Y Y Y Y Y Y Y Y Y Y Y Y
4.9 Y Y Y Y Y Y Y Y Y Y
7.75 Y Y Y Y Y Y Y Y Y
10 Y Y Y Y Y Y Y Y Y
21.2 Y Y Y Y Y Y Y Y Y

Extensive Range of Dimensions and Silicas
Based in the UK, Hichrom is a leading global manufacturer of HPLC and UHPLC
columns. We offer unrivalled experience in the manufacture of superior quality HPLC
columns, in an extensive range of dimensions from capillary to preparative. We are
also able to pack columns from any commercially available material. If you cannot
find the column dimensions/silica you require in the list above, please contact our
technical team who will be happy to check availability and discuss the option of a
custom manufactured column. We are highly experienced in the manufacture of
unique dimension/silica columns for specific applications and are able to offer many
products that are not listed in the catalogue or on the website.

Customer Supplied Packings
In addition to the wide range of materials listed in the catalogue, Hichrom can also
manufacture columns from any commercially available material and pack columns from
customer supplied materials. Please contact us to discuss this service. We will be pleased
to sign a confidentially agreement if required.Please contact Hichrom for further information.

Hichrom is one of the leading European manufacturers of HPLC columns. We have unrivalled experience in the manufacture of superior quality columns from microbore to preparative scale dimensions.