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NUCLEOSHELL RP 18plus

NUCLEOSHELL RP 18plus is a new core-shell C18 phase from Macherey-Nagel. It is available with particle sizes of 2.7 and 5m. Due to its monomeric bonding this phase offers hydrophobic characteristics with distinct polar selectivity. A special derivatisation process generates a medium density bonded silane with reduced steric selectivity compared to NUCLEOSHELL RP 18. Whereas NUCLEOSHELL RP 18 has an operable pH range of 1-11, the recommended pH range for NUCLEOSHELL RP 18plus is 2-9. NUCLEOSHELL RP 18plus is recommended for polar applications eg. antibiotics, water-soluble vitamins and organic acids.

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