Tel: +44 (0) 118 930 3660

GlycanPac

Thermo Scientific's GlycanPac columns are high performance HPLC/UHPLC columns specifically designed for structural, qualitative and quantitative analysis of glycans. They are designed for high resolution and high throughput analyses, with unique selectivity for biologically important glycans, either labelled or native, using either fluorescence or MS detection.

  • Unique glycan selectivity
  • Mixed-mode surface chemistry
  • Designed for high resolution and high throughput analyses
  • Compatible with fluorescence and MS detection

 

 GlycanPac phase specifications

PhaseRetention MechanismParticle Size (um)Pore Size (A)Surface area (m2/g)pH Range
GlycanPac AXH-1 WAX + HILIC 1.9 175 220 2 - 8
GlycanPac AXH-1 WAX + HILIC 3 120 300 2 - 8
GlycanPac AXR-1 WAX + RP 1.9 175 220 2 - 8

 

 GlycanPac AXH-1

is a high performance column for the simultaneous separation of glycans by charge, size and polarity. Weak anion-exchange (WAX) and HILIC retention mechanisms combine to give optimal selectivity and resolution power. The WAX functionality provides retention and selectivity for negatively charged glycans, while the HILIC mode facilitates the separation of glycans of the same charge according to their polarity and size.

 

GlycanPac AXR-1

UHPLC columns separate glycans according to charge, size and isomer structure. Weak anion-exchange (WAX) and reversed-phase (RP) retention mechanisms combine for optimal selectivity and ultra-high resolution for glycan separation. The WAX functionality separates glycans according to charge, whilst the RP property facilitates high resolution for glycans of the same charge according to their hydrophobicity, branching and isomerisation.

Literature:

  • GlycanPac AXH-1 column product specifications
  • GlycanPac AXR-1 column product specifications

                     

Or contact our Technical Support team