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Chiral Technologies:

 

CHIRALPAK and CHIRALCEL columns for SFC

Daicel polysaccharide CSPs are the most widely used columns for chiral SFC separations. In addition to faster separations, faster method development and improved column efficiency, SFC enables faster preparative separations, as isolated fractions are collected in smaller volumes of liquid.

As a general rule, all Daicel analytical immobilised and coated CHIRALPAK and CHIRALCEL HPLC columns can be used for SFC analysis. However, when purchasing an HPLC column for SFC use it is worth specifying this so that such columns can be evaluated under SFC conditions prior to shipment. 

 

In addition to the full HPLC column range, Chiral Technologies also offer a range of analytical columns specifically designed to meet the demands of high performance SFC. These include a range of shorter 100 x 4.6mm columns for fast analysis and screening in SFC and a newer range of 3mm i.d. (3um particle size) columns for both immobilised and coated phases.

Semi-preparative and preparative CHIRALPAK and CHIRALCEL SFC columns (10mm and 20mm i.d.) are packed specifically to withstand the higher pressures generated by SFC.

Screening using SFC is recommended on the four main immobilised phases (CHIRALPAK IA, IB, IC and ID) and the four main coated columns (CHIRALPAK AD and AS and CHIRALCEL OD and OJ), with varying concentrations of organic modifier.

In addition to the well established OD and OJ phases and the newer OX and OZ chlorinated phases, a range of complementary cellulose based CHIRALCEL phases are available, including OA, OB, OC, OF, OG and OK.

 

 CHIRALCEL material specifications

PhaseChiral selector

CHIRALPAK IA SFC, CHIRALPAK AD-H SFC

Amylose tris (3, 5-dimethylphenylcarbamate)

CHIRALPAK IB SFC, CHIRALCEL OD-H SFC

Cellulose tris (3, 5-dimethylphenylcarbamate)

CHIRALPAK IC SFC

Cellulose tris (3, 5-dichlorophenylcarbamate)

CHIRALPAK ID SFC

Amylose tris (3-chlorophenylcarbamate)

CHIRALPAK IE SFC

Amylose tris (3, 5-dichlorophenylcarbamate)

CHIRALPAK IF SFC, CHIRALPAK AZ-H SFC

Amylose tris (3-chloro, 4-methylphenylcarbamate)

CHIRALPAK AS-H SFC

Amylose tris ((S)-alpha-methylbenzylcarbamate)

CHIRALPAK AY-H SFC

Amylose tris (5-chloro-2-methylphenylcarbamate)

CHIRALCEL OJ-H SFC

Cellulose tris (4-methylbenzoate)

CHIRALCEL OX-H SFC

Cellulose tris (4-chloro-3-methylphenylcarbamate)

CHIRALCEL OZ-H SFC

Cellulose tris (3-chloro-4-methylphenylcarbamate)

 

 

Further technical information:

 

Catalogue information on CHIRALPAK and CHIRALCEL columns for SFC  


Other products from Chiral Technologies:

 

                     

 

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